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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR1
All Species:
15.45
Human Site:
S291
Identified Species:
28.33
UniProt:
Q8IVT5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVT5
NP_055053.1
921
102032
S291
P
R
T
P
P
P
P
S
R
K
V
F
Q
L
L
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
P334
I
P
S
Q
Q
R
S
P
L
L
S
E
R
S
L
Rhesus Macaque
Macaca mulatta
XP_001105629
926
102454
S293
P
R
T
P
P
P
P
S
R
K
V
F
Q
L
L
Dog
Lupus familis
XP_853953
898
99758
S293
P
R
T
P
P
P
P
S
R
K
V
F
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61097
873
96737
S279
P
R
T
P
P
P
P
S
R
K
V
F
Q
L
L
Rat
Rattus norvegicus
P14056
604
67533
K47
S
V
Y
D
S
L
D
K
A
L
K
V
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
P05625
647
73106
G90
M
K
A
L
K
V
R
G
L
Q
P
E
C
C
A
Frog
Xenopus laevis
P09560
638
71941
C81
S
G
M
S
L
H
D
C
L
M
K
S
L
K
V
Zebra Danio
Brachydanio rerio
XP_684771
890
98557
R296
R
T
P
P
P
P
S
R
K
L
L
N
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
E225
Q
L
T
P
D
M
C
E
V
S
T
T
H
S
G
Honey Bee
Apis mellifera
XP_393005
895
100160
S269
T
K
S
K
S
H
E
S
Q
L
A
N
R
L
E
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
A256
E
I
V
L
A
N
L
A
P
T
S
G
Q
S
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.3
98.2
89.1
N.A.
86.4
22.7
N.A.
20.4
24.1
23.1
43.3
N.A.
24.5
31.7
20.8
N.A.
Protein Similarity:
100
55.7
98.6
91.2
N.A.
89.3
36.8
N.A.
24.7
38.5
37.8
55.7
N.A.
41.4
47.2
36.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
0
0
0
26.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
0
13.3
6.6
40
N.A.
13.3
40
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
8
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
8
8
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
8
8
0
0
0
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
16
0
8
8
0
0
8
8
31
16
0
0
8
0
% K
% Leu:
0
8
0
16
8
8
8
0
24
31
8
0
16
47
47
% L
% Met:
8
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
16
0
0
0
% N
% Pro:
31
8
8
47
39
39
31
8
8
0
8
0
0
0
16
% P
% Gln:
8
0
0
8
8
0
0
0
8
8
0
0
39
0
0
% Q
% Arg:
8
31
0
0
0
8
8
8
31
0
0
0
24
0
0
% R
% Ser:
16
0
16
8
16
0
16
39
0
8
16
8
0
24
0
% S
% Thr:
8
8
39
0
0
0
0
0
0
8
8
8
0
0
0
% T
% Val:
0
8
8
0
0
8
0
0
8
0
31
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _